Yes, several characters die in the 2025 TV mini-series Star Wars: Tales of the Underworld, with notable deaths including Asajj Ventress and a key Inquisitor.

• Asajj Ventress: She is shown dead at the start of the series, with a scene where Jedi Quinlan Vos and Obi-Wan Kenobi lay her body to rest in a dark pool on the planet Dathomir. Ventress's death occurred prior to the events of the series, as she was believed dead at the time of Star Wars: The Bad Batch. The series reveals that though she was dead, she later returned in a typical Star Wars fashion, indicating a resurrection or survival beyond apparent death. Ventress's death originally happened off-screen in earlier lore, killed by Count Dooku during a complex relationship involving her and Quinlan Vos, as established previously in the Dark Disciple novel. Her death and resurrection add depth to her story arc in the underworld timeline of Star Wars.

• A Key Inquisitor: The show also features the death of a significant Inquisitor character. While not named specifically, this Inquisitor plays a role similar to the Eleventh Brother from Tales of the Jedi, and his death is depicted during the series. The circumstances involve typical confrontations with Jedi or bounty hunters common in the Star Wars universe. Although killed, there is speculation that this Inquisitor might return in future media, following a pattern in Star Wars where death is often not permanent.

No other main character deaths were detailed explicitly in the search results, but these two are the most significant known deaths featured in Tales of the Underworld so far.

In summary:

| Character | Death Circumstance | When | How | |-----------------|-------------------------------------------------------------|----------------------|-------------------------------------------| | Asajj Ventress | Killed by Count Dooku (off-screen, prior to series events) | Before series (early) | Death by lightsaber during betrayal; body laid to rest on Dathomir | | Key Inquisitor | Killed during series events | During the series | Killed in combat; details unspecified |

Both deaths reflect the darker and more dangerous environment of the Star Wars underworld portrayed in the 2025 series.