The episode begins with an outbreak of a virus called Explovid-23 spreading across Earth, causing those infected to become extremely irritable and rage-filled. The Planet Express crew is affected by the pandemic, and the Professor works on developing a vaccine to combat the virus. Meanwhile, conspiracy theories about the vaccine and the virus spread rapidly, with characters like Dr. Banjo promoting misinformation, which leads to widespread vaccine hesitancy among the population.

Leela contracts Explovid-23 and becomes symptomatic, showing signs of irritability and rage. Fry takes care of her, bringing her food while she is quarantined inside an "angry dome," a containment area for those infected. Despite Fry's efforts, Leela remains symptomatic, and the virus continues to spread.

Hermes becomes increasingly unhinged by the situation and, convinced that Explovid-23 is a form of zombieism, decides to seek a cure through voodoo magic. He travels to New New Orleans, a vibrant city with a strong voodoo culture, to investigate. There, Hermes encounters his rival Barbados, who runs the local "Voodoo HQ." Hermes shares his zombie theory with Barbados, who reveals that their voodoo practices are actually based on advanced biochemistry.

Barbados and his team test their "voodoo shots" on Hermes, which are designed to cure the virus. Hermes's wife assists in the process, and they descend into the depths of Voodoo HQ, which is revealed to be a high-tech laboratory rather than a mystical place. The shots begin to show promise as a cure for Explovid-23.

Meanwhile, the Omicronians, led by Lrrr, launch an invasion of Earth. During the invasion, Zap and Kif engage in a fight with each other rather than the invaders, highlighting the chaos and confusion caused by the virus and the pandemic. The Omicron variant of the virus spreads rapidly, exacerbating the situation.

Back at Planet Express, the Professor's exaggerated COVID swab test is introduced, and the crew continues to deal with the pandemic's effects. Amy vacillates between believing and dismissing misinformation about the virus and vaccine, reflecting the confusion and mixed messages prevalent during the pandemic.

As the episode progresses, the "voodoo" cure gains acceptance as it effectively targets the virus, convincing more people to get vaccinated. Dr. Banjo, despite his earlier misinformation, ultimately accepts the vaccine shot, acknowledging that no real science is involved in the cure, just as Hermes's voodoo approach was essentially advanced science disguised as magic.

The episode ends with the virus being brought under control through the combined efforts of science and the voodoo cure, the Omicronian invasion being thwarted, and the Planet Express crew returning to some semblance of normalcy. Fry and Leela's relationship remains strong, with Fry continuing to care for Leela throughout her illness. The episode closes on a note that blends satire of the COVID-19 pandemic with the show's characteristic humor and character-driven storytelling.

At the end of Futurama Season 8, Episode 7, "Rage Against the Vaccine," the Earth faces an invasion by the Omicronians who exploit the chaos caused by the mutated virus and widespread vaccine misinformation. The Planet Express crew, after navigating quarantine, conspiracy theories, and vaccine trials, ultimately confronts the viral threat and the invaders. The episode closes with Professor Farnsworth receiving a vaccination shot, symbolizing a hopeful step toward overcoming the pandemic crisis.

Expanding on the ending scene by scene:

The climax unfolds as the Omicronian invaders arrive on Earth, taking advantage of the confusion and anger fueled by rampant misinformation about the vaccine and the virus's mutations. Zapp Brannigan and Kif Kroker, instead of focusing on the external threat, are comically engaged in a furious fight against each other, blinded by their own rage, which highlights the internal discord among Earth's defenders.

Meanwhile, Hermes Conrad, after being led deeper into a mysterious building by Barbados Slim, discovers a high-tech laboratory that turns out to be the headquarters for a voodoo-themed vaccine research operation. Hermes's knowledge and his wife LaBarbara's assistance become crucial in developing a vaccine that can counter the virus's latest mutations. This scene emphasizes the blending of science and cultural elements in the fight against the pandemic.

Leela remains quarantined in the "Angry Dome," still symptomatic, but Fry bravely enters the dome to bring her food and support, showing his loyalty and care despite the risks. This personal moment contrasts with the larger chaos outside and underscores the human element amid the crisis.

As the virus mutates through various stages--from underground mutants to the general population and finally to the Omicronians themselves--the episode portrays the evolving nature of the pandemic threat. The multiple vaccine variants, including those developed by Farnsworth and Wernstrom, have different side effects, such as magnetic superpowers or aching shoulders, adding a layer of absurdity to the situation.

In the final moments, Professor Farnsworth receives his vaccination shot, which humorously injects through his arm into his torso, symbolizing the acceptance of science and the hope for a solution. Dr. Banjo, a recurring anti-vaxxer character, reluctantly accepts his shot as well, acknowledging the necessity despite his conspiratorial beliefs.

The episode closes with an inverted Arthur C. Clarke quote, a subtle nod to the show's sci-fi roots and a reflective touch on the nature of knowledge and belief during a crisis.

Regarding the fate of the main characters at the end:

• Professor Farnsworth is vaccinated, representing scientific progress and hope.
• Leela remains quarantined but supported by Fry, indicating ongoing struggle but personal care.
• Fry shows courage by entering the quarantine zone and supporting Leela.
• Hermes plays a key role in vaccine development, aided by his wife, highlighting his importance beyond bureaucratic duties.
• Zapp and Kif remain distracted by their personal conflict, missing the bigger threat.
• Dr. Banjo reluctantly submits to vaccination, showing a begrudging acceptance of reality.

The ending ties together the episode's themes of misinformation, mutation, and the social dynamics of a pandemic, concluding on a note of cautious optimism through vaccination and unity.

The episode "Rage Against the Vaccine" from Futurama Season 8, Episode 7 (2023) does not have a post-credits scene. None of the available detailed reviews, episode summaries, or video content related to this episode mention or show any post-credits or after-credits scene. The focus of the episode and its coverage is on the main plot about the COVID-19 pandemic satire, without any additional scenes after the credits roll.

Hermes becomes a central character who pursues a cure for the EXPLOVID-23 virus through voodoo magic. He travels to New New Orleans, seeking help from a voodoo organization run by his rival Barbados. Hermes believes the virus is 'zombie-based' and his involvement leads to discovering that the voodoo practices are actually a front for a high-tech biochemistry lab, which helps develop a vaccine. His story also explores his backstory with voodoo and zombies, adding depth to his character in this episode.

Dr. Banjo returns as an anti-vaxxer character who spreads conspiracy theories, including the false claim that 5G-enabled chips are in the vaccine. He represents the pseudo-intellectual opposition to vaccination and conspiracy theories prevalent during the COVID-19 pandemic. Despite his skepticism, he eventually accepts the vaccine shot, highlighting the episode's satirical take on misinformation.

The Omicronians, aliens from Omicron Persei 8, have their own variant of the EXPLOVID-23 virus and are involved in an invasion of Earth. Their variant spreads and causes chaos, and they are shown posting misinformation to weaken Earth for their invasion. There is also a comedic fight scene between Zap and Kif during the invasion, adding to the episode's humor.

The episode features multiple vaccine variants with distinct side effects: Professor Farnsworth's vaccine causes an aching shoulder, while Professor Wernstrom's vaccine gives people uncontrollable magnetic superpowers. These exaggerated effects parody the real-world variety of COVID-19 vaccines and public reactions to them.

The episode satirizes the social and media response by showing widespread misinformation, conspiracy theories, and distrust in news outlets. Social media is depicted as a tool for spreading false information, with characters like Jrrr fabricating stories to destabilize society. The episode also references common pandemic experiences such as lockdowns, video calls, and mask-wearing, using humor to critique the public's reaction to the crisis.

The Futurama episode "Rage Against the Vaccine" (Season 8, Episode 7, 2023) is generally suitable for a family audience but contains some content that might be potentially objectionable or upsetting for children or sensitive viewers.

Potentially sensitive aspects include:

• Satirical treatment of the COVID-19 pandemic and vaccines, including references to misinformation and public reactions, which might be confusing or distressing for younger children or those sensitive to pandemic-related topics.

• Scenes involving riots and anger, such as Bender joining a riot and aggressive behavior, which could be intense for sensitive viewers.

• Use of voodoo and supernatural elements tied to Hermes' storyline, which might be unsettling or culturally sensitive for some.

• Some crude humor and jokes, including references to cheating and possibly insensitive jokes related to cultural stereotypes, which may not be appropriate for all children.

• Mild violence and chaotic scenes, such as characters manning gun turrets and shooting at each other in rage, though presented in a comedic and exaggerated manner.

Overall, while the episode is comedic and satirical, its topical focus on the pandemic and related social issues, combined with some mature humor and chaotic scenes, suggests parental discretion is advised for younger or sensitive viewers. There are no reports of explicit content or severe violence, but the tone and themes may be challenging for some children.