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Chaos reigns at the natural history museum when night watchman Larry Daley accidentally stirs up an ancient curse, awakening Attila the Hun, an army of gladiators, a Tyrannosaurus rex and other exhibits.
Ben Stiller
as Larry Daley
Carla Gugino
as Rebecca
Dick Van Dyke
as Cecil
Mickey Rooney
as Gus
Bill Cobbs
as Reginald
Jake Cherry
as Nick Daley
Ricky Gervais
as Dr. McPhee
Robin Williams
as Theodore Roosevelt
Kim Raver
as Erica Daley
Patrick Gallagher
as Attila the Hun
Rami Malek
as Ahkmenrah
Pierfrancesco Favino
as Christopher Columbus
Charlie Murphy
as Taxi Driver
Steve Coogan
as Octavius
Mizuo Peck
as Sacajawea
Kerry van der Griend
as Neanderthal #1
Dan Rizzuto
as Neanderthal #2
Matthew Harrison
as Neanderthal #3
Jody Racicot
as Neanderthal #4
Paul Rudd
as Don
Anne Meara
as Debbie
Martin Christopher
as Lewis
Martin Sims
as Clark
Randy Lee
as Hun #1
Darryl Quon
as Hun #2
Gerald Wong
as Hun #3
Paul Cheng
as Hun #4
Teagle F. Bougere
as Teacher (Mike)
Pat Kiernan
as TV News Anchor
Nico McEown
as Friend #1
Meshach Peters
as Friend #2
Matthew Walker
as Politician
Jason McKinnon
as Irish Worker
Jono Lee
as Chinese Rail Worker
Jason Vaisvila
as Viking
Brad Garrett
as Easter Island Head (voice)
Crystal the Monkey
as Dexter
Che Landon
as Pretty Tourist Girl (uncredited)
Phil Proctor
as Moose (uncredited)
Gary Sievers
as Viking Warrior (uncredited)
Owen Wilson
as Jedediah Smith (uncredited)
Darren Shahlavi
as Roman (uncredited)
Miraida Rios
as (voice actor)
Ben Stiller
as Larry Daley
Carla Gugino
as Rebecca
Dick Van Dyke
as Cecil
Mickey Rooney
as Gus
Bill Cobbs
as Reginald
Jake Cherry
as Nick Daley
Ricky Gervais
as Dr. McPhee
Robin Williams
as Theodore Roosevelt
Kim Raver
as Erica Daley
Patrick Gallagher
as Attila the Hun
Rami Malek
as Ahkmenrah
Pierfrancesco Favino
as Christopher Columbus
Charlie Murphy
as Taxi Driver
Steve Coogan
as Octavius
Mizuo Peck
as Sacajawea
Kerry van der Griend
as Neanderthal #1
Dan Rizzuto
as Neanderthal #2
Matthew Harrison
as Neanderthal #3
Jody Racicot
as Neanderthal #4
Paul Rudd
as Don
Anne Meara
as Debbie
Martin Christopher
as Lewis
Martin Sims
as Clark
Randy Lee
as Hun #1
Darryl Quon
as Hun #2
Gerald Wong
as Hun #3
Paul Cheng
as Hun #4
Teagle F. Bougere
as Teacher (Mike)
Pat Kiernan
as TV News Anchor
Nico McEown
as Friend #1
Meshach Peters
as Friend #2
Matthew Walker
as Politician
Jason McKinnon
as Irish Worker
Jono Lee
as Chinese Rail Worker
Jason Vaisvila
as Viking
Brad Garrett
as Easter Island Head (voice)
Crystal the Monkey
as Dexter
Che Landon
as Pretty Tourist Girl (uncredited)
Phil Proctor
as Moose (uncredited)
Gary Sievers
as Viking Warrior (uncredited)
Owen Wilson
as Jedediah Smith (uncredited)
Darren Shahlavi
as Roman (uncredited)
Miraida Rios
as (voice actor)
