The five most popular story-related questions people ask about Sherlock & Daughter Season 1 are:

1. How does the dynamic between Sherlock Holmes and his newly introduced daughter Amelia develop throughout the season?
2. What are the main mysteries or cases Sherlock and Amelia work on together in Season 1?
3. How does the show balance classic Sherlock Holmes elements with the new family drama themes?
4. What are the key character traits and backgrounds of Amelia, and how do they contrast with Sherlock's?
5. How does the setting of Victorian London contribute to the atmosphere and storytelling in the series?

These questions focus on the character relationships, mystery elements, thematic balance, character development, and setting details that define the story content of the show, as reflected in viewer reviews and critiques.