The five most popular questions about the story content of Your Friends & Neighbors Season 1 Episode 1 'This Is What Happens' are:

1. Why did Andrew Cooper start stealing again despite the risks and consequences?
2. What is the nature of Cooper's relationship with his sister Miesa, and how does her mental health affect the story?
3. How does Cooper's unemployment and financial struggles influence his actions and decisions in the episode?
4. What role do Cooper's neighbors and their affluent lifestyle play in the unfolding events?
5. How does Cooper's past, including his relationship with his ex-wife Manny and his history of petty crime, impact the dynamics shown in the episode?

These questions focus on the character motivations, relationships, and plot developments specific to the episode's story, excluding general plot or ending inquiries.