The five most popular story-related questions people ask about The Librarians: The Next Chapter, Season 1, excluding the overall plot and ending, are:

1. Who is Vickram, the new Librarian, and what is his character like?
2. How do the new characters Lysa and Connor compare to previous Librarians, and what roles do they play?
3. What is the role and characterization of Charlie, the new Guardian, and how does she differ from past Guardians?
4. How does the show balance its monster-of-the-week format with the magical elements and humor?
5. What new magical adventures or artifacts are introduced in this season, and how do they drive the story?

These questions arise from viewers' interest in the new cast dynamics, character development, and the show's approach to continuing the franchise's tone and style with fresh elements.