In the ending of "Pineapple Express," Dale and Saul confront the drug dealers who are after them. After a chaotic and violent showdown, they manage to escape. The film concludes with Dale and his girlfriend, who have reconciled, and Saul, who has found a new sense of purpose, reflecting on their experiences.

As the climax of "Pineapple Express" unfolds, we find Dale Denton and Saul Silver cornered in a dilapidated house, surrounded by the menacing figures of drug dealers led by the ruthless Ted Jones. The tension is palpable as Dale, played by Seth Rogen, and Saul, portrayed by James Franco, realize the gravity of their situation. They are not just fighting for their lives; they are also grappling with the consequences of their choices and the bond that has formed between them throughout their misadventures.

The scene shifts to a chaotic confrontation in the house. Ted Jones, played by Gary Cole, and his henchmen are armed and ready for violence. Dale and Saul, armed with little more than their wits and a few makeshift weapons, prepare for a fight. The air is thick with anxiety as they exchange nervous glances, knowing that their survival depends on their ability to work together. The stakes are high, and the fear of death looms over them.

As the confrontation escalates, a series of comedic yet intense moments unfold. Dale and Saul's attempts to defend themselves lead to a series of slapstick mishaps, showcasing their ineptitude but also their determination. The chaos reaches a peak when they manage to turn the tables on their attackers, using the environment to their advantage. The fight is frenetic, filled with gunfire and physical comedy, illustrating the absurdity of their predicament.

In the midst of the chaos, we see a pivotal moment where Dale's character evolves. Initially portrayed as a passive character, he finds a surge of courage and takes decisive action to protect Saul. This shift highlights his growth throughout the film, as he transitions from a stoner with little ambition to someone willing to fight for his friend and his own life.

As the dust settles, Dale and Saul emerge from the wreckage of the house, battered but alive. They share a moment of relief and camaraderie, realizing that their bond has deepened through the ordeal. The film captures their emotional state, reflecting a mix of exhaustion, exhilaration, and a newfound appreciation for their friendship.

In the final scenes, we see Dale reconnecting with his girlfriend, who had been worried about him throughout the film. Their reunion is heartfelt, showcasing the importance of relationships and the impact of their experiences on personal growth. Saul, on the other hand, is left contemplating his future. He has found a sense of purpose beyond just being a stoner; he is now a survivor, ready to embrace whatever comes next.

The film concludes with a sense of closure for both characters. Dale and his girlfriend are seen together, hinting at a hopeful future, while Saul is left with the promise of new adventures. The ending encapsulates the themes of friendship, personal growth, and the absurdity of life, leaving the audience with a mix of laughter and reflection on the wild journey they have just witnessed.

The Pineapple Express strain of marijuana serves as a crucial plot device in the film. It is the rare strain that Dale Denton, played by Seth Rogen, smokes and is later linked to a murder he witnesses. The strain's unique characteristics and its association with the characters' misadventures drive the narrative forward, leading to a series of comedic and dangerous situations.

Dale Denton, a process server, meets Saul Silver, a laid-back marijuana dealer played by James Franco, when he goes to buy weed. Their relationship evolves from a simple client-dealer dynamic to a close friendship as they navigate the chaos that ensues after Dale witnesses a murder. Saul's carefree attitude contrasts with Dale's anxiety, creating a comedic yet supportive bond as they face danger together.

The confrontation with the drug dealers is triggered when Dale witnesses a murder committed by a corrupt cop and a drug lord named Ted Jones. After accidentally leaving behind a joint of Pineapple Express at the crime scene, Dale's connection to the murder is established. This leads to a series of frantic attempts to evade the drug dealers, culminating in a climactic showdown where Dale and Saul must confront Ted and his henchmen.

Red, played by Danny McBride, is Saul's friend and a fellow drug dealer who becomes embroiled in the chaos when Dale and Saul seek refuge at his house. Red's over-the-top personality and reckless behavior add to the comedic elements of the film. He provides both comic relief and a sense of danger, as his involvement with the drug dealers escalates the conflict and leads to more absurd situations.

Dale's relationship with his girlfriend Angie, played by Amber Heard, is initially strained due to his lack of commitment and maturity. As the events unfold, Dale's experiences with Saul and the dangers they face force him to confront his own shortcomings. By the end of the film, he realizes the importance of being honest and taking responsibility, leading to a more mature understanding of his relationship with Angie.